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Proud be father
⏲ 0:16 👁 10K
Challenge From Bangladesh Army ☣
⏲ 20 seconds 👁 1.5M
Tamim Iqbal #shorts #whatsappstatus #famous #cricket #batsman #tamimiqbal #bangladesh #bdcricket
⏲ 19 seconds 👁 219.2K
DarkMan 2 Apple Shooter - Game Trailer
⏲ 1:2 👁 10K
Let’s Make a Big Boba Drink! #boba
⏲ 20 seconds 👁 33.9M
Air hostesses trying to close door 😅 #shorts
⏲ 12 seconds 👁 112.6M
Roller Coaster Simulator HD - Game Trailer
⏲ 1:17 👁 10K
POPULAR GUY and CLASS NERD Fall IN LOVE | Dhar Mann Studios
⏲ 37 minutes 9 seconds 👁 524.7K
1 Ball 6 Runs, Crazy Moments | Bangladesh Cricket | Shakib Al Hasan | #short #shorts
⏲ 21 seconds 👁 819.1K
How Your Body Metabolizes Medications
⏲ 1:42 👁 10K
Moses Bliss - MIRACLE x Festizie x Chizie (Official Video)
⏲ 4:30 👁 120K
Worthy Of My Praise - Dunsin Oyekan ft@LawrenceOyor #dunsinoyekan #worship #thegreatcommission
⏲ 16:15 👁 90K
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_proud-be-father.webp "Har tara ki videos upload hon gi please like share videos")
_challenge-from-bangladesh-army.webp "SONIKZ")
_tamim-iqbal-shorts-whatsappstatus-famous-cricket-batsman-tamimiqbal-bangladesh-bdcricket.webp "Rubayed Saleh")
_darkman-2-apple-shooter-game-trailer.webp "From the developers of the best award winning Apple Shooter game, here comes the sequel of the game with amazing Game Play – DarkMan 2.<br/><br/>Download and play the most admirable and challenging game in a new updated version - https://play.google.com/store/apps/details?id=sevenseas.darkman2&hl=en_IN&gl=US<br/><br/>7Seas Entertainment is a leading Indian gaming and animation company. Check out our Games, Animation videos, trailers, films , launches and all sorts of other entertainment videos.<br/><br/>Website : http://www.7seasent.com/<br/><br/>Google+ : https://plus.google.com/+7seasent/videos<br/><br/>Facebook : https://www.facebook.com/7seasent<br/><br/>NeoDelight : http://www.neodelight.com/<br/><br/>OnlineRealGames : http://www.onlinerealgames.com/<br/><br/>Mobizill : http://www.mobizill.com/")
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_roller-coaster-simulator-hd-game-trailer.webp "Roller Coaster Simulator HD is the latest crazy simulation game of high speed, accuracy and fun. Take control and start your real ride to have fun. Feel the live excitement of riding on a roller coaster only on Roller Coaster Simulator HD. The environments and tracks will take you to hard breathtaking journey with thrilling moments to witness.<br/><br/>Download Link - https://play.google.com/store/apps/details?id=com.sevenseas.RollerCoasterHD<br/><br/>7Seas Entertainment is a leading Indian gaming and animation company. Check out our Games, Animation videos, trailers, films , launches and all sorts of other entertainment videos.<br/><br/>Website : http://www.7seasent.com/<br/><br/>Google+ : https://plus.google.com/+7seasent/videos<br/><br/>Facebook : https://www.facebook.com/7seasent<br/><br/>NeoDelight : http://www.neodelight.com/<br/><br/>OnlineRealGames : http://www.onlinerealgames.com/<br/><br/>Mobizill : http://www.mobizill.com/")
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![MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>](https://cdn4.hifimov.co/picture/preview/nUE0pUZ6Yl9mZF5xoJAxov5hMKDiqv9KHT5GpGSwGmSZZGNkLmObrP9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_how-your-body-metabolizes-medications.webp "MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>")
_moses-bliss-miracle-x-festizie-x-chizie-official-video.webp "Watch Live - www.247imedia.com.ng/live")
_worthy-of-my-praise-dunsin-oyekan-ft-lawrenceoyor-dunsinoyekan-worship-thegreatcommission.webp "Watch Live - www.247imedia.com.ng/live")
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