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The solid tumor microenvironment is immunosuppressive and poses a significant obstacle to achieving clinical success with various immunotherapies. Most notably, immune checkpoint pathways, including PD-1, PD-L1, and CTLA-4, allow tumors to evade the body’s usual immune reaction, leading to disease progression. Checkpoint blockade via monoclonal antibodies results in augmented T-cell activation and proliferation to enhance the anti-tumor immune response and has revolutionized the field, but not
Immuno-Oncology for Solid Tumors: Overcoming Barriers in the Tumor Microenvironment
⏲ 46 min 70 sec ✓ 20-Sep-2019
union UNAPECLE
Monoclonal antibodies, technics use in immunotherapy
⏲ 3 minutes 1 second 👁 308
Basic Science Series
Monoclonal Antibody Therapy | Immunotherapy | Immunity | Basic Science Series
⏲ 6 minutes 6 seconds 👁 181
A virus is an infectious agent that can only replicate within a host organism. Viruses can infect a variety of living organisms, including bacteria, plants, and animals. Viruses are so small that a microscope is necessary to visualize them, and they have a very simple structure.<br/>If an antigen enters the body and B-cells recognize it (either from having had the disease before or from being vaccinated against it), B-cells will produce antibodies. When antibodies attach to an antigen (think a lock–key configuration), it signals other parts of the immune system to attack and destroy the invaders.
Virus and human immunity response
⏲ 1:33 👁 80K
Cancer Support Community
Ask Ruby: What is a Monoclonal Antibody?
⏲ 1 minute 43 seconds 👁 209
curetoday
Shaji Kumar on Treatment-Related Adverse Events From Monoclonal Antibodies
⏲ 45 seconds 👁 565
inherited properties of red blood cells (erythrocytes) as determined by the presence or absence of the antigens A and B, which are carried on the surface of the red cells. Persons may thus have type A, type B, type O, or type AB blood. The A, B, and O blood groups were first identified by Austrian immunologist Karl Landsteiner in 1901. See blood group.<br/><br/>Blood containing red cells with type A antigen on their surface has in its serum (fluid) antibodies against type B red cells. If, in transfusion, type B blood is injected into persons with type A blood, the red cells in the injected blood will be destroyed by the antibodies in the recipient’s blood. In the same way, type A red cells will be destroyed by anti-A antibodies in type B blood. Type O blood can be injected into persons with type A, B, or O blood unless there is incompatibility with respect to some other blood group system also present. Persons with type AB blood can receive type A, B, or O blood.
ABO Blood Typing
⏲ 2:23 👁 5K
Mount Sinai Health System
What You Need to Know About Monoclonal Antibody Therapy
⏲ 6 minutes 50 seconds 👁 293
Zero To Finals
How do monoclonal antibodies work? Rituximab, infliximab, adalimumab and others
⏲ 11 minutes 49 seconds 👁 376.9K
Day 3 track 2 Session: Pathogen Specific Biologics for Infectious DiseasesnnImmunotherapy for infectious diseases was invented in the 19th century but fell out of favor when antibiotics were discovered and developed in the middle of the 20th century. In fact, to date there is only one single monoclonal antibody in clinical use for an infectious disease. However, several are now in development. Coupled with rapid diagnostics these pathogen-specific agents may well serve to bring us back to the fu
D3 13:30 T2- Steven Projan, MedImmune; René Russo, Arsanis; Fred Tenover, Stanford; and David Martin, AvidBiotics Corp.
⏲ 34 min 85 sec ✓ 24-Feb-2017
WCNC
How monoclonal antibody therapy can help treat COVID-19 patients
⏲ 1 minute 12 seconds 👁 246
Shomu's Biology
Cancer treatment using monoclonal antibody
⏲ 9 minutes 34 seconds 👁 26K
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